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>Is it real?

Morphing a device into a drug
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Case Studies

#3. Is it real?

The new management at a leading platform biotechnology company was confronted with a project which sought to leverage the company's core technology to accelerate and improve the accuracy of portfolio screening decisions made by major pharma manufacturers.

While the market need was obvious, the ability of the technology to satisfactorily meet the challenge on a profitable basis was at issue. The project was consuming an increasing amount of precious cash and had reached a point where a significantly greater commitment would be required to proceed. Strong project advocates within the organization were backed with ambitious projections for the technology. The Street, meanwhile, was having difficulty even understanding the potential business.

After an immersion into the technology by the client's expert team, the BDF engagement team developed preliminary business models for the technology which addressed the need to validate the still nascent technology and to operate an ultimately viable business. Critical was the need to balance investment risk, cash consumption, and potential return.

The BDF team then took "sanitized" business propositions to potential pharma customers for a real world assessment of the technology and underlying business propositions. Since there were perhaps two hundred individuals in the world who could seriously gauge the proposition, the BDF team used its extensive pharmaceutical and biotech industry connections to identify those few key individuals whose expert opinion and/or decision-making authority would truly have a compelling influence on a purchase decision. Once the decision making structure was validated, in-depth interviews were conducted with heads of research, technology development team leaders, and front line scientists as most appropriate to the organization.

While potential customers applauded the client’s efforts, it quickly emerged that the actual volume of procedures in which the technology would be employed were far fewer than in the clients original projections. Customers noted that the client's projections represented an "ideal" situation, often discussed, but rarely seen in actual practice. Customers, too, had predictable reservations about the reliability of the technology vis-a-vis an alternative which many had recently embraced - but also offered concrete suggestions for how to more rapidly demonstrate its validity.

After an extensive analysis of the findings, BDF then returned to the client's Board with two deliverables:

  • A difficult recommendation to terminate the project and redirect resources into its two more promising businesses which offered greater shareholder value
  • In the event the client elected to proceed, revised business models, projections, and technology validation strategies that would buffer client risk and more rapidly address lingering market concerns.

BDF's biotech clients are typically populated by exceptional individuals, passionate about their work and determined to do what's best for their companies. BDF can help in making sure that that effort and determination are directed against the activities that will ultimately create the greatest value.

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